FiltraLinX® benchtop TFF system adopts a modular design, equipped with membrane filter holders of different specifications, to meet filtration area requirements of 0.1-0.5 m2 or 0.5-2.5 m2. According to the process requirements, the circulating pump can be flexibly configured with a rotor pump or a diaphragm pump. The benchtop TFF filteration system is designed to be compact and practical, with an automatic control system for flow rate and pressure to achieve automatic control of TMP and Delta P, thereby realizing automated operations such as concentration, diafiltration, desalting and dealcoholization of bioproducts such as antibodies, vaccines, blood products, and gene therapy drugs. Featuring automated operation, cost-effectiveness, and compliance with regulations related to data integrity, the benchtop TFF filter system is an ideal choice for laboratory research, pilot-scale production, clinical drug production, and GMP production stages.
Vaccines
Gene therapy
Cell therapy
Nanomedicines
Monoclonal antibodies
Recombinant proteins
Blood products
Various specifications available: 0.1-0.5 m2 and 0.5-2.5 m2 benchtop ultrafiltration membrane filtration
Capable of using hollow fiber filters
Equipped with PLC, weighing unit, manual valve, circulating pump, flow meter, pressure sensor and other components to control TMP and Delta P, enabling automated production operations
Equipped with 316L stainless steel filtration tank for sample loading and collection
Equipped with flexible process sample interfaces, compatible with single-use storage and mixing bags for product loading and collection
Equipped with peristaltic pump for feeding to achieve equal-volume diafiltration
Reserved interface for membrane integrity testing
Mature automatic control software that complies with data integrity requirements of GMP production
Can be equipped with online pH, online conductivity detection, and other instruments
Support CIP, SIP and IT membrane integrity testing and NWP water flux detection functions
| Membrane area | Membrane filters: 0.1-0.5 m2 | Membrane filters: 0.5-2.5 m2 |
| In-process tank | 5 L | 10 L |
| Equipment dimensions and weight | 950 × 560 × 1450 mm and 130 kg | 1250 × 560 × 1450 mm and 180 kg |
| Automatic control level | Automatic control | |
| Operating pressure | Max. 5 bar | |
| stem pressure resistance | Max. 6 bar | |
| Pipeline fittings | SS 316L; Ra ≤ 0.4 μm | |
| Sanitary connection | TC chuck | |
| Manual valve | PP, SS 316L | |
| Flow detection | Permeate end, electromagnetic flow meter; retentate end; electromagnetic flow meter | |
| Operation mode | Automatic feedback control | |
| Operating temperature | 4-40 °C @ PP; 4-60 °C @ SS 316L | |
| Min. circulation volume | 0.1-0.5 m2 benchtop model: minimum circulation volume ~ 200 mL. 0.5-2.5 m2 benchtop model: minimum circulation volume ~ 400 mL. | |
| Language | Chinese, English | |
| Material (liquid contact part) | Common and classic materials in the pharmaceutical industry such as 316 L, Polymer (USP class VI or FDA), EPDM, Santoprene elastomer, medical, Grade epoxy, silicone. | |
* Customization available upon request. For details, please consult the local sales or call the hotline 4000589000.
Comply with FDA 21CFR Part 11 requirements for electronic records and electronic signatures
Comply with audit trail requirements
Bilingual operating interface: Chinese, English
Hierarchical alarm management
Three-level permissions management
Data backup and restore
Clock synchronization
Display process parameter trend chart, and generate reports in PDF
SCADA system interface to realize the data integration of MES system
**Please be advised that this product is only available for sale and after-sales support in certain regions. For further details, kindly consult with your local sales representative. Thank you for your understanding.
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