Through the magnetic coupling mechanism, the motor drives the single-use stirring blades in the stirring bag to rotate, which can meet various needs such as liquid-liquid mixing, solid-liquid mixing, etc.
BioHub® BM Single-use Magnetic Mixing System has a nice and neat appearance and is easy to clean, handle and use. The system is specially designed for production mixing in biotechnology and pharmaceuticals to facilitate lab research, process development, and GMP production.
The system provides an ideal solution for efficient solid/liquid mixing applications. As a flexible mobile mixing platform, the system provides effective and sustainable single-use mixing solutions for different volumes and application types. The system has demonstrated excellent performance in buffer and medium preparation.
• Wide volume range
The BioHub® BM Single-use Magnetic Mixing System covers various volumes, including 50 L, 100 L, 200 L, 400 L, 500 L, 650 L, 1000 L, 1500 L, 2000 L, 2500 L, and 3000 L, so as to meet the requirements of scale-up from R&D to mass production; other volumes can be customized.
• Wide working volume range
The working volume is usually 20%–110% of the mixing system volume.
• Low residual liquid
With an inclined bottom at an angle of 2–5° , the liquid outlet is located at the lowest level of the whole equipment, ensuring a low residual liquid ( ≤ 20 mL) and reducing the loss of feed liquid (dwell volume ≤ 2.5 L for 2500 L and ≤ 3 L for 3000 L).
• Precise mixing
The motor is from Oriental Motor. The rotation speed precision is ±2 rpm. The motor is at a fixed time and fixed speed, can be instantly started and stopped, and no pre-heating or magnetizing is required.
• Polished and wire-drawn
The whole device is made of SS304L with anti-fingerprint polishing (Ra ≤ 0.8 μm), preventing injuries to soft bags.
• Compact structure
The equipment has a compact plug-and-run structure design and there is no need to install a driver or controller. The structural design is friendly to users. The shelf and handle can well protect the weight sensor.
• No condensation
Dimple jackets at four sides enables the temperature of the feed liquid to be controlled in a short time. Also, insulation layers are provided outside the jackets, which helps to avoid condensation when the temperature of the feed liquid is lower or higher than the ambient temperature, meeting the requirements of clean workshops.
• Easy cleaning
No obvious arrangement of wires can be observed on the surface of the equipment. All wiring is arranged inside the equipment (with waterproof connectors) for a neat appearance, making it easy to transfer the equipment inside a workshop and clean it after use.
• Modular design
Various modules are available for different customer demands, including mixing, weighing, temperature control, pH, cond, peristaltic pump, etc. All core components and parts are from high-end brands, ensuring the stable control of critical parameters.
• Stable hardware design
The design of window/manual control on the side of the mixing bin facilitates the installation of bags and allows the visual inspection of the mixing status.
The control interface and mixing bin height are reasonably designed for easier operation.
The rotatable electric-control mixing bin makes it easier to use and clean from multiple angles.
The liquid outlet line and safety valve are added to meet the needs of safety and convenience.
• Reliable software control
The standard configuration of the genuine Windows 10 Enterprise Edition, Advantech IPC, and Siemens PLC ensures smooth operations.
Permission management, audit trail, batch data export, data integrity, and related functions are available, meeting the data integrity requirements of 21CFR Part 11 and satisfying the requirements for GMP production.
Due to the flexible process formula function newly added, customers can manually add various standard formulas. Also, the standard formula recording function coming with the program can save the customer's repeated efforts, reducing the risk of use.
• Independent control of production
BioLink's manufacturing site covers an area of 10,000 m2 and is equipped with independent sheet metal cutting equipment, bending equipment, polishing equipment,etc. From raw materials and steel materials to product delivery, the entire production process is independently controlled by BioLink to assure product quality and control the delivery time.
• Medium preparation
• Buffer preparation
• Downstream intermediate product processing
• Bulk purification
• Semi-finished product preparation
The BioHub® BM Single-use Magnetic Mixing System works through a magnetic coupling motor to drive the single-use stirring paddles in the mixing bag to rotate, and is equipped with physical shaft seals. This system is safe, reliable, stable and efficient. Working together with a stainless steel bin, it can meet various liquid-liquid mixing and solid-liquid mixing needs, suitable for medium preparation, buffer preparation, intermediate mixing, semi-finished product preparation, and final pharmaceutical products mixing.
The mixing system consists of a stainless steel bin, a control system, a magnetic mixing motor, and a single-use mixer bag. The modular design allows for flexible combinations of different functions on demand, such as mixing, weighing, feedback-controlled temperature monitoring, pH, and conductivity, while supporting high levels of customization to the complex needs of customers. The system also provides three-level permissions and electronic signature to meet the data integrity needs of pharmaceutical customers.
MX50 | MX100 | MX200 | MX400 | MX500 | MX1000 | MX1500 | MX2000 | MX2500 | MX3000 | |
Dimension (mm) | 1087*679 *1165 | 1187*779 *1165 | 1318*914 *1213 | 1451*1045 *1313 | 1501*1099 *1413 | 1718*1315 *1648 | 2022*1408 *1724 | 2697*1452 *1568 | 2697*1452 *1738 | 2697*1452 *1918 |
Weight (kg) | Unjacket- ed:190 Jacketed: 225 | Unjacket- ed:215 Jacketed: 260 | Unjacket- ed:250 Jacketed: 320 | Unjacket- ed:310 Jacketed: 400 | Unjacket- ed:335 Jacketed: 435 | Unjacket- ed:455 Jacketed: 646 | Unjacket- ed:626 Jacketed: 895 | Unjacket- ed:985 Jacketed: 1295 | Unjacket- ed:1075 Jacketed: 1420 | Unjacket- ed:1165 Jacketed: 1545 |
Material | SS304L | |||||||||
Roughness | Ra ≤ 0.8 μm | |||||||||
Jacket | Optional | |||||||||
Heat exchange area (m²) | 0.5 | 0.64 | 1.02 | 1.38 | 1.8 | 3.1 | 4.05 | 6.2 | 7 | 7.8 |
Volume in the jacket (L) | 2.8 | 3.2 | 4.3 | 8.7 | 12.4 | 20.6 | 26.4 | 44.2 | 52.6 | 64.8 |
Maximum working pressure in the jacket (bar) | 6 | 6 | 6 | 6 | 6 | 6 | 6 | 6 | 6 | 6 |
Mixing unit | The system is equipped with Oriental Motor and magnetic coupling mixing, with a speed accuracy of ± 5 rpm | |||||||||
Weighing unit | METTLER hygienic weighing module, with a weighing accuracy of 0.3% | |||||||||
Online temperature module | WIKA | |||||||||
Online conduc- tivity module | Hamilton | |||||||||
Online pH module | Hamilton | |||||||||
Data integrity | Three-level permission, audit trail, batch record export, interface with a central console, etc. |
MX50 | MX100 | MX200 | MX400 | MX500 | MX650 | MX1000 | MX2000 | |
Dimension(mm) | 1071*630*1165 | 1168*735*1165 | 1273*830*1165 | 1434*977*1325 | 1581*1130*1263 | 1581*1130*1423 | 1725*1270*1600 | 1770*1285*2830 |
Weight (kg) | Unjacketed:199 jacketed:227 | Unjacketed:215 jacketed:255 | Unjacketed:245 jacketed: 300 | Unjacketed:297 jacketed:375 | Unjacketed:219 jacketed:405 | Unjacketed:365 jacketed:465 | Unjacketed:468 jacketed:652 | Unjacketed:1085 jacketed:1410 |
Material | SS304L | |||||||
Roughness | Ra ≤ 0.8 μm | |||||||
Jacket | Optional | |||||||
Heat exchange area (m²) | 0.5 | 0.64 | 1.02 | 1.39 | 1.8 | 2.2 | 3.1 | 5.6 |
Volume in the jacket (L) | 2.8 | 3.2 | 4.3 | 8.7 | 12.4 | 16.6 | 20.6 | 44.2 |
Maximum working pressure in the jacket (bar) | 6 | 6 | 6 | 6 | 6 | 6 | 6 | 6 |
Mixing unit | The system is equipped with Oriental Motor and magnetic coupling mixing, with a speed accuracy of ± 5 rpm | |||||||
Weighing unit | METTLER hygienic weighing module, with a weighing accuracy of 0.3% | |||||||
Online temperature module | Hamilton | |||||||
Online conduc- tivity module | Hamilton | |||||||
Online pH module | Hamilton | |||||||
Data integrity | Three-level permission, audit trail, batch record export, interface with a central console, etc. |
BM Integrated Mixer:
Name Rules for BM Single-use Integrated Magnetic Mixing System
Product Name: Volume + Integrated mixing system
Cat. No.: A + B
Drawing No.: A-GAD | ||||||||||||||||||||||
A | B | |||||||||||||||||||||
Initial letter | Series No. | Volume | Jacket | Screen | pH module | Cond module | Temperature module | Pinter | ||||||||||||||
Z (Mettler sensor + Self-developed transmitter) | BMP | 0050 | Y | I: Advantech IPC | H: Hamilton | H: Hamilton | T: Surface mount | P: Yes | ||||||||||||||
A (Mettler sensor + Mettler transmitter) | BMC | 0100 | N | S: Siemens HMI | M: Mettler + M80 | M: Mettler + M80 | C: Plug-in | N: No | ||||||||||||||
K (Mettler module + Self- developed transmitter) | BMM (Magnetic coupling) | 0200 | T: Siemens 12’’IPC | K: No | Brand is Brightek | |||||||||||||||||
R (Mettler sensor + Mettler transmitter) | BMF (Magnetic levitation) | 0300 | K: Siemens 15’’IPC | |||||||||||||||||||
N (No weighing) | 0400 | M: Kunlun Tongtai | P: No | C: No | C for standard (default WIKA) | |||||||||||||||||
Z for standard | 0500 | I for standard | H for standard | H for standard | ||||||||||||||||||
0650 | Note: BMM indicates compatibility with Merck Generation II, using magnetic coupling. BMF indicates compatibility with Merck Generation I magnetic levitation. There are two motor options: imported Lev and domestic Cheer. Catalog numbers are not differentiated; please specify clearly when ordering, with Cheer being the preferred choice. | |||||||||||||||||||||
1000 | ||||||||||||||||||||||
1500 | ||||||||||||||||||||||
2000 | ||||||||||||||||||||||
2500 | ||||||||||||||||||||||
3000 |
Mixing tank
Name | Form | Cat.No. | Configuration | Description |
Single-use mixing tank MX50 | Cubic stainless steel tank | BMPMX50L001 | Unjacketed | BMP split series |
Cubic stainless steel tank | BMPMX50L002 | Unjacketed, with weighing | ||
Cubic stainless steel tank | BMPMX50L003 | Jacketed | ||
Cubic stainless steel tank | BMPMX50L004 | Jacketed, with weighing | ||
Single-use mixing tank MX100 | Cubic stainless steel tank | BMPMX100L001 | Unjacketed | |
Cubic stainless steel tank | BMPMX100L002 | Unjacketed, with weighing | ||
Cubic stainless steel tank | BMPMX100L003 | Jacketed | ||
Cubic stainless steel tank | BMPMX100L004 | Jacketed, with weighing | ||
Single-use mixing tank MX200 | ![]() | BMPMX200L001 | ![]() | |
Cubic stainless steel tank | BMPMX200L002 | Unjacketed, with weighing | ||
Cubic stainless steel tank | BMPMX200L003 | Jacketed | ||
Cubic stainless steel tank | BMPMX200L004 | Jacketed, with weighing | ||
Single-use mixing tank MX400 | Cubic stainless steel tank | BMPMX400L001 | Unjacketed | |
Cubic stainless steel tank | BMPMX400L002 | Unjacketed, with weighing | ||
Cubic stainless steel tank | BMPMX400L003 | Jacketed | ||
Cubic stainless steel tank | BMPMX400L004 | Jacketed, with weighing | ||
Single-use mixing tank MX500 | ![]() | BMPMX500L001 | ![]() | |
Cubic stainless steel tank | BMPMX500L002 | Unjacketed, with weighing | ||
Cubic stainless steel tank | BMPMX500L003 | Jacketed | ||
Cubic stainless steel tank | BMPMX500L004 | Jacketed, with weighing | ||
Single-use mixing tank MX650 | Cubic stainless steel tank | BMPMX650L001 | Unjacketed | |
Cubic stainless steel tank | BMPMX650L002 | Unjacketed, with weighing | ||
Cubic stainless steel tank | BMPMX650L003 | Jacketed | ||
Cubic stainless steel tank | BMPMX650L004 | Jacketed, with weighing | ||
Single-use mixing tank MX1000 | ![]() | BMPMX1000L001 | ![]() | |
Cubic stainless steel tank | BMPMX1000L002 | Unjacketed, with weighing | ||
Cubic stainless steel tank | BMPMX1000L003 | Jacketed | ||
Cubic stainless steel tank | BMPMX1000L004 | Jacketed, with weighing | ||
Single-use mixing tank MX1500 | ![]() | BMPMX1500L001 | ![]() | |
Cubic stainless steel tank | BMPMX1500L002 | Unjacketed, with weighing | ||
Cubic stainless steel tank | BMPMX1500L003 | Jacketed | ||
Cubic stainless steel tank | BMPMX1500L004 | Jacketed, with weighing | ||
Single-use mixing tank MX2000 | ![]() | BMPMX2000L001 | ![]() | |
Cubic stainless steel tank | BMPMX2000L002 | Unjacketed, with weighing | ||
Cubic stainless steel tank | BMPMX2000L003 | Jacketed | ||
Cubic stainless steel tank | BMPMX2000L004 | Jacketed, with weighing |
Name | Form | Cat.No. | Configuration | Description |
Single-usemixingtank MX50 | Cubicstainlesssteeltank | BMCMX50L001 | Unjacketed | BMCsplitseries |
Cubicstainlesssteeltank | BMCMX50L002 | Unjacketed, with weighing | ||
Cubicstainlesssteeltank | BMCMX50L003 | Jacketed | ||
Cubicstainlesssteeltank | BMCMX50L004 | Jacketed, with weighing | ||
Single-usemixingtank MX100 | Cubicstainlesssteeltank | BMCMX100L001 | Unjacketed | |
Cubicstainlesssteeltank | BMCMX100L002 | Unjacketed, with weighing | ||
Cubicstainlesssteeltank | BMCMX100L003 | Jacketed | ||
Cubicstainlesssteeltank | BMCMX100L004 | Jacketed, with weighing | ||
Single-usemixingtank MX200 | Cubicstainlesssteeltank | BMCMX200L001 | Unjacketed | |
Cubicstainlesssteeltank | BMCMX200L002 | Unjacketed, with weighing | ||
Cubicstainlesssteeltank | BMCMX200L003 | Jacketed | ||
Cubicstainlesssteeltank | BMCMX200L004 | Jacketed, with weighing | ||
Single-usemixingtank MX500 | Cubicstainlesssteeltank | BMCMX500L001 | Unjacketed | |
Cubicstainlesssteeltank | BMCMX500L002 | Unjacketed, with weighing | ||
Cubicstainlesssteeltank | BMCMX500L003 | Jacketed | ||
Cubicstainlesssteeltank | BMCMX500L004 | Jacketed, with weighing | ||
Single-usemixingtank MX1000 | Cubicstainlesssteeltank | BMCMX1000L001 | Unjacketed | |
Cubicstainlesssteeltank | BMCMX1000L002 | Unjacketed, with weighing | ||
Cubicstainlesssteeltank | BMCMX1000L003 | Jacketed | ||
Cubicstainlesssteeltank | BMCMX1000L004 | Jacketed, with weighing | ||
Single-usemixingtank MX1500 | Cubicstainlesssteeltank | BMCMX1500L001 | Unjacketed | |
Cubicstainlesssteeltank | BMCMX1500L002 | Unjacketed, with weighing | ||
Cubicstainlesssteeltank | BMCMX1500L003 | Jacketed | ||
Cubicstainlesssteeltank | BMCMX1500L004 | Jacketed, with weighing | ||
Single-usemixingtank MX2000 | Cubicstainlesssteeltank | BMCMX2000L001 | Unjacketed | |
Cubicstainlesssteeltank | BMCMX2000L002 | Unjacketed, with weighing | ||
Cubicstainlesssteeltank | BMCMX2000L003 | Jacketed | ||
Cubicstainlesssteeltank | BMCMX2000L004 | Jacketed, with weighing | ||
Single-usemixingtank MX2500 | Cubicstainlesssteeltank | BMCMX2500L001 | Unjacketed | |
Cubicstainlesssteeltank | BMCMX2500L002 | Unjacketed, with weighing | ||
Cubicstainlesssteeltank | BMCMX2500L003 | Jacketed | ||
Cubicstainlesssteeltank | BMCMX2500L004 | Jacketed, with weighing |
Link With Us Now!