BioHub^® BM Single-use Magnetic Mixing System

BioHub^® BM Single-use Magnetic Mixing System has a nice and neat appearance and is easy to clean, handle and use. The system is specially designed for production mixing in biotechnology and pharmaceuticals to facilitate lab research, process development, and GMP production.

The system provides an ideal solution for efficient solid/liquid mixing applications. As a flexible mobile mixing platform, the system provides effective and sustainable single-use mixing solutions for different volumes and application types. The system has demonstrated excellent performance in buffer and medium preparation.

Video of BM Single-use Magnetic Mixing System

Features of BioHub^® BM Single-use Magnetic Mixing System

•    Wide volume range

The BioHub^® BM Single-use Magnetic Mixing System covers various volumes, including 50 L, 100 L, 200 L, 400 L, 500 L, 650 L, 1000 L, 1500 L, 2000 L, 2500 L, and 3000 L, so as to meet the requirements of scale-up from R&D to mass production; other volumes can be customized.

•    Wide working volume range

The working volume is usually 20%–110% of the mixing system volume.

•    Low residual liquid

With an inclined bottom at an angle of 2–5° , the liquid outlet is located at the lowest level of the whole equipment, ensuring a low residual liquid ( ≤ 20 mL) and reducing the loss of feed liquid (dwell volume ≤ 2.5 L for 2500 L and ≤ 3 L for 3000 L).

•    Precise mixing

The motor is from Oriental Motor. The rotation speed precision is ±2 rpm. The motor is at a fixed time and fixed speed, can be instantly started and stopped, and no pre-heating or magnetizing is required.

•    Polished and wire-drawn

The whole device is made of SS304L with anti-fingerprint polishing (Ra ≤ 0.8 μm), preventing injuries to soft bags.

•    Compact structure

The equipment has a compact plug-and-run structure design and there is no need to install a driver or controller. The structural design is friendly to users. The shelf and handle can well protect the weight sensor.

•    No condensation

Dimple jackets at four sides enables the temperature of the feed liquid to be controlled in a short time. Also, insulation layers are provided outside the jackets, which helps to avoid condensation when the temperature of the feed liquid is lower or higher than the ambient temperature, meeting the requirements of clean workshops.

•    Easy cleaning

No obvious arrangement of wires can be observed on the surface of the equipment. All wiring is arranged inside the equipment (with waterproof connectors) for a neat appearance, making it easy to transfer the equipment inside a workshop and clean it after use.

•   Modular design

Various modules are available for different customer demands, including mixing, weighing, temperature control, pH, cond, peristaltic pump, etc. All core components and parts are from high-end brands, ensuring the stable control of critical parameters.

•   Stable hardware design

The design of window/manual control on the side of the mixing bin facilitates the installation of bags and allows the visual inspection of the mixing status.

The control interface and mixing bin height are reasonably designed for easier operation.

The rotatable electric-control mixing bin makes it easier to use and clean from multiple angles.

The liquid outlet line and safety valve are added to meet the needs of safety and convenience.

•    Reliable software control

The standard configuration of the genuine Windows 10 Enterprise Edition, Advantech IPC, and Siemens PLC ensures smooth operations.

Permission management, audit trail, batch data export, data integrity,  and related functions are available, meeting the data integrity requirements of 21CFR Part 11 and satisfying the requirements for GMP production.

Due to the flexible process formula function newly added, customers can manually add various standard formulas. Also, the standard formula recording function coming with the program can save the customer's repeated efforts, reducing the risk of use.

•    Independent control of production

BioLink's manufacturing site covers an area of 10,000 m2 and is equipped with independent sheet metal cutting equipment, bending equipment, polishing equipment,etc. From raw materials and steel materials to product delivery, the entire production process is independently controlled by BioLink to assure product quality and control the delivery time.

Applications of BioHub^® BM Single-use Magnetic Mixing System

•   Medium preparation

•   Buffer preparation

•   Downstream intermediate product processing

•   Bulk purification

•   Semi-finished product preparation

Advantages of BioHub^® BM Single-use Magnetic Mixing System

The BioHub^® BM Single-use Magnetic Mixing System works through a magnetic coupling motor to drive the single-use stirring paddles in the mixing bag to rotate, and is equipped with physical shaft seals. This system is safe, reliable, stable and efficient. Working together with a stainless steel bin, it can meet various liquid-liquid mixing and solid-liquid mixing needs, suitable for medium preparation, buffer preparation, intermediate mixing, semi-finished product preparation, and final pharmaceutical products mixing.

The mixing system consists of a stainless steel bin, a control system, a magnetic mixing motor, and a single-use mixer bag. The modular design allows for flexible combinations of different functions on demand, such as mixing, weighing, feedback-controlled temperature monitoring, pH, and conductivity, while supporting high levels of customization to the complex needs of customers. The system also provides three-level permissions and electronic signature to meet the data integrity needs of pharmaceutical customers.

Specifications of BioHub^® BM Single-use Magnetic Mixing System

Technical Parameters of BMC Integrated Mixer

Technical Parameters of BMP Integrated Mixer

Ordering Information：

BM Integrated Mixer：

Name Rules for BM Single-use Integrated Magnetic Mixing System

Product Name: Volume + Integrated mixing system

Cat. No.: A + B

BM Split Series

Mixing tank

Name	Form	Cat.No.	Configuration	Description
Single-use mixing tank MX50	Cubic stainless steel tank	BMPMX50L001	Unjacketed	BMP split series
	Cubic stainless steel tank	BMPMX50L002	Unjacketed, with weighing
	Cubic stainless steel tank	BMPMX50L003	Jacketed
	Cubic stainless steel tank	BMPMX50L004	Jacketed, with weighing
Single-use mixing tank MX100	Cubic stainless steel tank	BMPMX100L001	Unjacketed
	Cubic stainless steel tank	BMPMX100L002	Unjacketed, with weighing
	Cubic stainless steel tank	BMPMX100L003	Jacketed
	Cubic stainless steel tank	BMPMX100L004	Jacketed, with weighing
Single-use mixing tank MX200	Cubic stainless steel tank	BMPMX200L001	Unjacketed
	Cubic stainless steel tank	BMPMX200L002	Unjacketed, with weighing
	Cubic stainless steel tank	BMPMX200L003	Jacketed
	Cubic stainless steel tank	BMPMX200L004	Jacketed, with weighing
Single-use mixing tank MX400	Cubic stainless steel tank	BMPMX400L001	Unjacketed
	Cubic stainless steel tank	BMPMX400L002	Unjacketed, with weighing
	Cubic stainless steel tank	BMPMX400L003	Jacketed
	Cubic stainless steel tank	BMPMX400L004	Jacketed, with weighing
Single-use mixing tank MX500	Cubic stainless steel tank	BMPMX500L001	Unjacketed
	Cubic stainless steel tank	BMPMX500L002	Unjacketed, with weighing
	Cubic stainless steel tank	BMPMX500L003	Jacketed
	Cubic stainless steel tank	BMPMX500L004	Jacketed, with weighing
Single-use mixing tank MX650	Cubic stainless steel tank	BMPMX650L001	Unjacketed
	Cubic stainless steel tank	BMPMX650L002	Unjacketed, with weighing
	Cubic stainless steel tank	BMPMX650L003	Jacketed
	Cubic stainless steel tank	BMPMX650L004	Jacketed, with weighing
Single-use mixing tank MX1000	Cubic stainless steel tank	BMPMX1000L001	Unjacketed
	Cubic stainless steel tank	BMPMX1000L002	Unjacketed, with weighing
	Cubic stainless steel tank	BMPMX1000L003	Jacketed
	Cubic stainless steel tank	BMPMX1000L004	Jacketed, with weighing
Single-use mixing tank MX1500	Cubic stainless steel tank	BMPMX1500L001	Unjacketed
	Cubic stainless steel tank	BMPMX1500L002	Unjacketed, with weighing
	Cubic stainless steel tank	BMPMX1500L003	Jacketed
	Cubic stainless steel tank	BMPMX1500L004	Jacketed, with weighing
Single-use mixing tank MX2000	Cubic stainless steel tank	BMPMX2000L001	Unjacketed
	Cubic stainless steel tank	BMPMX2000L002	Unjacketed, with weighing
	Cubic stainless steel tank	BMPMX2000L003	Jacketed
	Cubic stainless steel tank	BMPMX2000L004	Jacketed, with weighing