info@biolink.com
+86-400-058-9000
CN
Products
Application & Solutions
Single-Use Bioprocess Solutions Monoclonal Antibody Production Vaccine Production mRNA Production
Support
FAQ Validation Service
Resource
Blog White Paper
Company
About Us Facilities Career Company News
Contact Us
Search
×
Single-Use Bioprocess Products Cell Culture Products Protein Chromatography Processing Filtration
Single-Use Bioprocess Bags and Bottles Single-Use Mixing System Aseptic Connect & Disconnect Bioprocess Supporting Vessels
BioHub®2D Single-use Storage bags BioHub® 3D Single-use Storage Bags NovaLinX® Nuclease-free Single-Use Bioprocess Bags BioHub® Single-Use Storage Bottles BioHub® MB Single-Use Mixing Bags BioHub® S Sterile Sampling Bags BioHub® S Sterile Sampling Bottles BioHub® BM Single-Use Magnetic Mixing System BioHub® DS Single-Use Desktop Mixing System BioHub® Single-Use Split Desktop Mixing System BioHub® Sealer BioHub® Welder BioHub® SC Sterile Cutter 3D Round Plastic Lab Support Bucket 3D Square Plastic Lab Folding Bucket 3D Stainless Steel Lab Support Barrel 2D Plastic Lab Tray 2D Cryoprotective Lab Case 2D Stainless Steel Lab Tray CytoLinX® GB 1-20 L Benchtop Glass Bioreactors CytoLinX® BR 50-2000 L Single-Use Bioreactor CytoLinX® WB Single-Use Rocking Bioreactor CytoLinX® WB Single-Use Cell Therapy Bags CytoLinX® WB Single-Use Cell Culture Bags Chrom-LinX® Laboratory Scale Empty Chromatography Columns Chrom-LinX® Manual Compression Chromatography Column Chrom-LinX® Auto Automated Chromatography Column PuriLinX® Benchtop Chromatography System ChromaX ™ Geldex Prepacked Column Chrom-Trap® & Chrom-Screen® Prepacked Column Chromstar® FF Resins for Size Exclusion Chromatography Chromstar® CL Resins for Size Exclusion Chromatography Chromstar® B Resins for Size Exclusion Chromatography Geldex® PG Series Resins for Size Exclusion Chromatography Puredex® G Series Resins for Size Exclusion Chromatography Puredex® LH-20 Resins for Size Exclusion Chromatography Maxtar® Resins for Ion Exchange Chromatography Maxtar® HR Ion Exchange Chromatography MaXtar® HR XL Resins for Ion Exchange Chromatography Chromstar® BB Resins for Ion Exchange Chromatography Chromstar® FF Ion Exchange Chromatography Resins Chromstar® HP Ion Exchange Chromatography Resins Chromstar® XL Resins for Ion Exchange Chromatography Puredex® Ion Exchange Chromatography Resins MaXtar® ARPA Affinity Chromatography Resins MaXtar® rProtein A Affinity Chromatography Resins MaXtar® Protein G Affinity Chromatography Resins rProtein A Chromstar® FF Affinity Chromatography Resins Protein G Chromstar® 4FF Affinity Chromatography Resins Protein G Chromstar® HP Affinity Chromatography Resins Ni Chromstar® Affinity Chromatography Resins IMAC Chromstar® Affinity Chromatography Resins MaXtar® Chelating Affinity Chromatography Resins Chelating Chromstar® FF Affinity Chromatography Resins Glutathione Chromstar® Affinity Chromatography Resins MaXtar® PlasmidCap HR Affinity Chromatography Resins PlasmidCap Chromstar® HP Affinity Chromatography Resins MaXtar® Heparin Affinity Chromatography Resins Heparin Chromstar® Affinity Chromatography Resins Benzamidine Chromstar® 4FF Affinity Chromatography Resins MaXtar® Blue Affinity Chromatography Resins Blue Chromstar® Affinity Chromatography Resins NHS Activated Chromstar® 4FF Affinity Chromatography Resins CNBr Activated Chromstar® Affinity Chromatography Resins MaXtar® Hydrophobic Chromatography Resins MaXtar® HR Hydrophobic Chromatography Resins Chromstar® FF Hydrophobic Chromatography Resins Chromstar® HP Hydrophobic Chromatography Resins MaXtar® MMC Multimodal Chromatography Resins Maxtar® COLL Multimodal Chromatography Resins Maxtar® MMA Multimodal Chromatography Resins Hydroxyapatite BaronCHT Type I&2 Multimodal Chromatography Resin Maxgo® 15S Polymer Chromatography FiltraLinX® Depth Filter Holder (Type P3C) Depth Filtration Bioprocess Fixture Type M
E-mail
Ion Exchange Chromatography

Ion Exchange Chromatography

In the downstream separation and purification process of biopharmaceuticals, chromatography is one of the indispensable separation methods. BioLink provides customers with 5 different chromatography solutions, including gel filtration chromatography, ion exchange chromatography, affinity chromatography, hydrophobic chromatography and multimodal chromatography. In addition, BioLink also produces chromatography columns and prepacked columns from laboratory to industrial grade. We focus on providing customers with high-quality products, professional solutions and comprehensive after-sales services.

Types of Ion Exchange Chromatography

Maxtar<sup>®</sup> Resins for Ion Exchange Chromatography
Ion exchange chromatography medium with high flow rate, low back pressure and high capacity.
Maxtar® Resins for Ion Exchange Chromatography
Maxtar<sup>®</sup> HR Ion Exchange Chromatography
Ion-exchange chromatography media with high resolution.
Maxtar® HR Ion Exchange Chromatography
MaXtar<sup>®</sup> HR XL Resins for Ion Exchange Chromatography
Ion-exchange chromatography media with ultra-high capacity and high resolution.
MaXtar® HR XL Resins for Ion Exchange Chromatography
Chromstar<sup>®</sup> BB Resins for Ion Exchange Chromatography
Ion exchange chromatography medium with large particle size agarose base frame, suitable for the separation process of macromolecular substances, high impurity content or samples with huge volumes.
Chromstar® BB Resins for Ion Exchange Chromatography
Chromstar<sup>®</sup> FF Ion Exchange Chromatography Resins
Agarose-based ion exchange chromatography media with high flow rates
Chromstar® FF Ion Exchange Chromatography Resins
Chromstar<sup>®</sup> HP Ion Exchange Chromatography Resins
High-resolution ion-exchange chromatography media for fine separations.
Chromstar® HP Ion Exchange Chromatography Resins
Chromstar<sup>®</sup> XL Resins for Ion Exchange Chromatography
Agarose-based ion-exchange chromatography medium with ultra-high capacity.
Chromstar® XL Resins for Ion Exchange Chromatography
Puredex<sup>®</sup> Ion Exchange Chromatography Resins
Dextran-Based Ion Exchange Chromatography Media.
Puredex® Ion Exchange Chromatography Resins

How To Select The Appropriate Chromatography Resin For My Own Process?

To select a suitable chromatography medium and chromatography mode, we need to clarify the purpose of chromatography and the isoelectric point PI (charge property) of the target product. The PI of the target product can be obtained by calculating the target product sequence (theoretical isoelectric point), or by capillary isoelectric focusing electrophoresis (CIEF) (actual isoelectric point). Separation of substances based on the difference in charge between the target product and impurities in a buffer with a specific pH value. According to different chromatographic purposes, two modes can be selected for the ion exchange chromatography process: (1) flow-through mode: the target product does not bind to the packing material, and impurities are bound to the chromatography packing material as much as possible; (2) combined elution mode: The target product is combined with the filler, and then eluted with a certain concentration of salt.

FAQs of Ion Exchange Chromatography

Q What is the principle of ion-exchange chromatography?

A

Ion exchange chromatography is a chromatography method that separates substances according to the difference in charge properties of different biomolecules. The ion exchange chromatography medium is composed of agarose/dextran/polymer matrix coupled with ligands with positive and negative charges. The medium with negative charge is called cation exchange chromatography medium, which can bind positively charged proteins; the medium with negative charge is called anion exchange chromatography medium, which can bind negatively charged proteins.

FAQ

Q How many chromatography resin can BioLink produce per year?

A

The chromatographic medium manufacturing facility for BioLink is situated in Lanzhou City, Gansu Province, and spans a total area of more than 7,000 square meters. The factory is in charge of producing purification and cell culture items such chromatography packing materials and microcarriers, with a total investment of more than 100 million yuan and close to 100 workers. The base now contains a production line for 500L and 1000L chromatography packaging, as well as a well-equipped laboratory for quality testing (which has earned ISO9001:2015 quality management system accreditation). The plant's 80,000 liters per year total capacity is envisaged.

FAQ

Link With Us Now!

Want to know more about BioLink bioprocessing products? Feel free to contact BioLink now!
Email
info@biolink.com
Phone
+86-400-058-9000
ADDRESS
News & Events
New Product | BioLink CytoLinX<sup>®</sup> GB Benchtop Bioreactor
08 Dec 2023
Read More +
New Product | BioLink CytoLinX® GB Benchtop Bioreactor
Compatibility Considerations for Single-use Technology in ADC Coupling Process
07 Dec 2023
Read More +
Compatibility Considerations for Single-use Technology in ADC Coupling Process
Extractables & Leachables: What's the Difference? How to Deal with It?
06 Dec 2023
Read More +
Extractables & Leachables: What's the Difference? How to Deal with It?
Products
Single-Use Bioprocess Products Cell Culture Products Protein Chromatography Processing Filtration
Application & Solutions
Single-Use Bioprocess Solutions Monoclonal Antibody Production Vaccine Production mRNA Production
Resource
Blog White Paper

Quick Links

Company Contact Us Validation Service FAQ
Contact Us
Email:
info@biolink.com

ADDRESS 1:

• BioLink Biological Applied Technologies Trade and Development (Shanghai) Co., Ltd.

• Building A&B 650 Chengfeng Road
Shanghai China 201200

ADDRESS 2:

• BioLink Application System GmbH

• Die Sang 6C，D-61191 Rosbach vor der Höhe，Germany
County court Friedberg Hesse, HRB 10155
USt-IdNr.: DE360068643

Copyright © Bio-Link All Rights Reserved.
Sitemap | Privacy Policy | 琼ICP备2023004837号-1
Products
Single-Use Bioprocess Products Cell Culture Products Protein Chromatography Processing Filtration
Application & Solutions
Single-Use Bioprocess Solutions Monoclonal Antibody Production Vaccine Production mRNA Production
Resource
Blog White Paper
Quick Links
Company Contact Us Validation Service FAQ
Contact Us
E-mail:
info@biolink.com Tel:
+86-400-058-9000
ADDRESS:
Copyright © Bio-Link All Rights Reserved.
Sitemap Privacy policy