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purilinx benchtop chromatography system 3
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PuriLinX® Benchtop Chromatography System

PuriLinX® is a benchtop chromatography system suitable for laboratory scale. It has high basic configuration, accurate and stable flow, high pressure resistance, and sensitivity in detection. The software has complete functions to meet the needs of various chromatography process development. Integrating functions such as instrument control, method editing, data analysis, standard curve, report generation, user permissions management, and audit trail, the software complies with relevant FDA/GLP/GMP regulations.


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Features of PuriLinX® Benchtop Chromatography System

  • High configuration (dual-pump and double-bubble sensor, dual-pump back pressure valve, column valve,        multi-channel loading valve, multi-channel outlet valve, and DAD ultraviolet detector), to meet diverse needs of chromatography process development

  • Classic duplex plunger parallel pump with reliable control and mechanical components, providing high accuracy and long-term stability

  • Detector adopting modular design, with independent coupled light source and highly sensitive polychromator spectral analysis system

  • External flow path design to avoid intersection with circuits, preventing accidental liquid leakage from damaging electrical components and prolonging the service life of the equipment

  • Humanized design of the instrument shell, elegant appearance, easy to operate and maintain

  • Linkage control of instrument and software, supporting wireless connection; user-friendly system software in line with the habits of laboratory personnel, supporting custom editing


Main Modules of PuriLinX® Benchtop Chromatography System

  • Pump system

With a classic duplex plunger parallel pump and reliable control and mechanical components, the system runs stably for a long time and provides accurate flow output.

  • Small dead volume of the pulse damper

  • Advanced cam technology and a double piston mechanism, providing virtually pulse-free fluid delivery

  • Specially designed for chromatographic separation and liquid phase analysis, featuring a large flow range, high accuracy, and small pulse

  • Standard fluid path materials: stainless steel and PEEK


  • DAD detector

DAD400 is an ultraviolet diode array detector specially developed for fields such as chromatography, environmental protection, and online monitoring.

The detector adopts a modular and separate design, has an independent coupled light source and a highly sensitive polychromator spectral analysis system, uses comprehensive methods to suppress stray light and circuit noise, and has a good dynamic range and excellent resolution.

  • Czerny-Turner polychromator spectral analysis system

  • The optical fiber is used to connect the flow cell, effectively isolating the heat source and facilitating maintenance

  • Multiple wavelengths can be set simultaneously

  • No mechanical motion parts, excellent stability

  • Rich output interfaces, easy to adapt


  • Bubble sensor

The ultrasonic bubble sensor is a standardized and easy-to-use sensor specially developed to achieve online fluid bubble monitoring in laboratories and processes, requiring no ultrasonic couplants.

  • Requiring no couplants, non-contact detection

  • No damage to the sample

  • Flexible and easy to use, dual-color LED indicator light


Collection rack

The new generation of general component collector can be used alone or in combination with a protein purification system.

  • Collection type: 96-well plate, 13 mm test tube rack, 16 mm test tube rack, 30 mm test tube rack

  • The test tube rack tray is applicable to all collection types, with no need to be changed

  • Matching other domestic and foreign generators, the instrument provides a wealth of external interfaces and a separate touch-screen control system

No.

Interface

description

No.

Interface

description


1

Power interface


5

Trigger interface

(electrical level/short

circuit/relay)

2

Network cable interface

6

Analog input interface

3

RJ12 interface


7

Solenoid valve data cable interface

4

COM serial port

(232/485)


Mixer

Mixing is performed by a dynamic, electromagnetically driven mixer, and the volume of the mixing pool is 2 mL

pH detector (including temperature compensation)

Detection range: pH: 0 – 14; detection precision: 0.1 pH

Conductivity detector (including temperature compensation)

Detection range: 0 –999.999 mS/cm; detection precision: ±2%



PuriLinX® Software Control — Smart Power

Smart Power is a specially developed intelligent and easy-to-use control system software that adopts a separate component design to enable customers to quickly master the skills of using the software.

PuriLinX® Benchtop Chromatography System


  • Result analysis:

The software provides comprehensive analysis functions such as spectrum comparison, peak analysis, column   efficiency analysis, and result export, and provides effective data analysis support for small-scale screening and process scale-up studies.

PuriLinX® Benchtop Chromatography System


  • Data storage:

Automatic backup to ensure data security

PuriLinX® Benchtop Chromatography System


  • Method editing:

Text editing to meet more complicated requirements for method editing

PuriLinX® Benchtop Chromatography System

Specifications of PuriLinX® Benchtop Chromatography System

Configuration option

Name

Technical parameters





















Standard configuration





PuriLinX infusion pump

PuriLinX® 36

PuriLinX® 100

Dual-pump system flow rate range:

0.01 – 36 mL/min;

pressure resistance range:

0 – 34.5 MPa (5000 psi);

flow accuracy: ±1.5%

Dual-pump system, flow rate range:

0.01 – 100 mL/min;

pressure resistance range:

0 – 10.3 MPa (1500 psi);

flow accuracy: ±1.5%

Flow rate repeatability: RSD ≤ 0.5%

Gradient type: linear, isocratic, stagewise gradient, gradient

ratio can be modified online

Inlet channel

4 channels: A1, A2, B1, B2

Bubble sensor

Ultrasonic detection, two sensors (A/B), standard configuration

Mixer

Electromagnetically driven mixer

Injection valve

High-pressure 6-way valve, supporting load, inject, and waste modes

Column valve

High-pressure 6-way valve, supporting upflow, downflow, and bypass modes


DAD detector

DAD400 has variable four-wavelength with a detection range

of 190-400 nm, enables direct reading of full spectrum, and

can detect four arbitrary wavelengths simultaneously

Wavelength range: 190 –400 nm

Channel: quadruple channel

Wavelength accuracy: 1 nm

PH online sensor

Range: 0 – 14;

accuracy: ±0.1;

temperature compensation: yes

Conductivity online sensor

Range: 0 –999.99 ms/cm;

accuracy: ±2%;

temperature compensation: yes

Pressure sensor

Pre-column pressure monitoring

Online filter

20 μm PP filter disc


Component collector module

Collection type: 1-way liquid waste,

1-way collection by collector

Placement of: 4 96-well plates; 2 13-mm test tube racks;

2 16-mm test tube racks; 2 30-mm test tube racks

Accessory package

Including pipeline, connector, maintenance tool, instructions

for use, and dongle, etc.

Control system

Control system (including computer, keyboard, mouse,

English and Chinese operating software)

can achieve 24-h uninterrupted operation





Configuration selection

Buffer inlet valve

9-channel: pump A: A1-1 to A1-6, A2; pump B: B1, B2

Outlet valve

6-channel: 1-way liquid waste, 4-way bulk collection, 1-way collection by collector


Sample pump

SP36D: flow rate range 0.01-36mL/min, pressure resistance

range 0-34.5MPa, flow rate accuracy ±1.5%.

SP100D: flow rate range 0.01-100mL/min, pressure resistance

range 0-10.3MPa, flow rate accuracy ±1.5%.

Four column position valve

Can connect four chromatography columns at the same time, support upflow, downflow, bypass


Ordering Information of PuriLinX® Benchtop Chromatography System

BLKX3601

PuriLinX 36D

36 mL dual-pump system, 2 inlets for pump A, 2 inlets for pump B,

1 automatic collection outlet, 1 waste liquid outlet, 1 bulk collection outlet

4 inlets,

3 outlets

BLKX3602

PuriLinX 36S

36 mL dual-pump system, 6+1 inlets for pump A, 2 inlets for pump B,

1 automatic collection outlet, 1 waste liquid outlet, 1 bulk collection outlet

9 inlets,

3 outlets

BLKX3603

PuriLinX 36M

36 mL dual-pump system, 2 inlets for pump A, 2 inlets for pump B,

1 automatic collection outlet, 1 waste liquid outlet, 4 bulk collection outlets

4 inlets,

6 outlets

BLKX3604

PuriLinX 36L

36 mL dual-pump system, 6+1 inlets for pump A, 2 inlets for pump B,

1 automatic collection outlet, 1 waste liquid outlet, 4 bulk collection outlets

9 inlets,

6 outlets

BLKX1001

PuriLinX 100D

100 mL dual-pump system, 2 inlets for pump A, 2 inlets for pump B,

1 automatic collection outlet, 1 waste liquid outlet, 1 bulk collection outlet

4 inlets,

3 outlets

BLKX1002

PuriLinX 100S

100 mL dual-pump system, 6+1 inlets for pump A, 2 inlets for pump B,

1 automatic collection outlet, 1 waste liquid outlet, 1 bulk collection outlet

9 inlets,

3 outlets

BLKX1003

PuriLinX 100M

100 mL dual-pump system, 2 inlets for pump A, 2 inlets for pump B,

1 automatic collection outlet, 1 waste liquid outlet, 4 bulk collection outlets

4 inlets,

6 outlets

BLKX1004

PuriLinX 100L

100 mL dual-pump system, 6+1 inlets for pump A, 2 inlets for pump B,

1 automatic collection outlet, 1 waste liquid outlet, 4 bulk collection outlets

9 inlets,

6 outlets


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