MaXtar® PlasmidCap HR is a thiophilic aromatic adsorption chromatography resin. Thiophilic affinity chromatography works by using the interaction between electron donors and acceptors to separate and purify target molecules. This interaction can be strengthened in a high-salt environment and weakened in a low-salt environment. MaXtar® PlasmidCap HR can selectively bind to closed-loop supercoiled plasmid DNA but not to open-loop plasmid DNA. Therefore, it can be used to prepare high-quality plasmid DNA.
Unlike PlasmidCap Chromstar HP chromatography resin, MaXtar® PlasmidCap HR conjugates the sulfur-containing compound 2-mercaptopyridine to a new highly rigid matrix, which provides better pressure-flow performance for large-scale separation and purification of plasmid DNA, bringing added flexibility in process design and improved productivity. Also, finer particle sizes can provide better resolution.
| Product | Feature | Mean particle size (μm) | Max. flow velocity (cm/h) | Quantity | Product code | |||||||
| MaXtar® PlasmidCap HR | High binding capacity High flow velocity High resolution For separation of supercoiled plasmid DNA | 40 | 300 | 25 mL | 1031-1821 | |||||||
| 100 mL | 1031-1822 | |||||||||||
| 500 mL | 1031-1823 | |||||||||||
| 1 L | 1031-1824 | |||||||||||
| 5 L | 1031-1825 | |||||||||||
| 10 L | 1031-1826 | |||||||||||
| 20 L | 1031-1827 | |||||||||||
**Please be advised that this product is only available for sale and after-sales support in certain regions. For further details, kindly consult with your local sales representative. Thank you for your understanding.
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