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Downstream Bioprocesses-the Role of Filtration


Use of Processing Filtration:

In downstream bioprocessing, Bioprocess Filtration is used to remove impurities and contaminants from the bioprocessing product. The function of processing filtration is to ensure the final product is of high quality and meets specific requirements, such as regulatory requirements and customer specifications.


Processing filtration functions:

Particle removal: 

Processing filtration can remove particles, such as bacteria, cells, and debris, from the bioprocess products.


Virus removal: 

Processing filtration can remove viruses, which can be present in the bioprocessing product, to ensure the product is safe and free of infectious agents.


Clarification: 

Processing filtration can clarify the bioprocessing product, removing suspended particles and improving the appearance and stability of the product.


Concentration: 

Processing filtration can be used to concentrate the bioprocessing product, increasing the overall yield of the process.


Sterilization: 

Processing filtration can be used to sterilize the bioprocessing product, ensuring that the final product is free of bacteria, spores, and other microorganisms.

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