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BioHub® DS Single-use Desktop Mixing System

The BioHub® DS Single-use Desktop Mixing System is a dedicated stirring device designed for small-volume liquid handling and desktop applications. This equipment, equipped with a control system, is compatible with various commonly used small-volume specifications, including 2L, 5L, 10L, 20L, 30Land more. It offers convenient operation and meets a wide range of requirements such as liquid-liquid mixing, solid-liquid mixing, and high-viscosity mixing. The system is designed to assist in research, process development, and other application scenarios.




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In biopharmaceutical process, small-volume mixing is required throughout the entire production process while large-volume equipment cannot realize such mixing. Therefore, BioLink launched a desktop mixing system for small-volume liquid mixing. The system with a nice and neat appearance is easy to clean and operate. It facilitates the small-volume mixing in lab research and process development. Applicable processes include plasmid mixing, intermediate product mixing, semi-finished product preparation, and drug product preparation.


Video of DS Single-Use Desktop Mixing System

Features of BioHub® DS Single-use Desktop Mixing System

  • The split design allows multi-split control to reduce the production cost

  • The mixing tanks are available in 2 L, 5 L, 10 L, 20 L, 30 L, so as to meet the mixing requirements of small-volume valuable feed liquids

  • Stainless steel and acrylic options are available for the mixing bins

  • Data integrity is compliant with 21CFR Part 11, satisfying the GMP requirements


Application of BioHub® DS Single-use Desktop Mixing System

  • Preparation of culture media and buffer solutions in Cell and Gene Therapy (CGT).

  • Homogenization of multiple plasmids prior to viral transfection in gene therapy.

  • Mixing of intermediate products.

  • Preparation of semi-finished products.

  • Homogenization of multi-valent vaccine formulations.


Specifications of BioHub® DS Single-use Desktop Mixing System

BioHub® DS Single-Use Desktop Mixing System, produced by BioLink, are made of multi-layer coextruded film as the raw material. This single use mixing bag ensures extremely low gas permeability, excellent chemical compatibility, biological compatibility, and good physical strength, making it safe for various biopharmaceutical process fluid preparation and storage. The stirring blade adopts a high-strength magnet with secondary encapsulation, ensuring complete sealing of the magnet. This, combined with different stirring blades, provides efficient mixing. When paired with BioLink's disposable tubing components, it meets the requirements for different processes and fluids.

Technical Parameters of Split Desktop Mixing System

Equipment ParametersIP RatingIP54
Power Supply220V 50HZ * Adjustable according to region
Power Consumption220 W
Current3A
Control Signal24VDC
Minimum Theoretical
Mixing Volume (L)		Specification2L tank                                             0.20L
5L tank                                             0.25L
10L tank                                           0.56L
20L tank                                           0.95L
SensorWeighingMETTLER TOLEDO
pHHamilton pH electrode, VP8 connector
CondHamilton Cond electrode, VP8 connector
TemperatureColliHigh, PT100, 0-150℃
OthersDO electrode (optional)
Speed ParametersSpeed Range0-400rpm
Speed Accuracy
(No Load)		±2rpm

Technical Parameters of Integrated Desktop Mixing System

Equipment ParametersPower supply220V 50HZ * Adjustable according to region
Power Consumption150 W
Current3A
Control Signal24VDC
Speed ParametersSpeed Range0-300rpm
Speed Accuracy
(No Load)		±2rpm


Ordering Information for Consumables

Single-use Split Desktop Mixing System：

Product NameCat. No.Note
Desktop controllerCB-DS-001AMCGS HMI（10''）+PLC+magnetic coupling
Desktop controllerCB-DS-001BMCGS HMI（10''）+PLC+magnetic levitation
Desktop controllerCB-DS-002ASiemens HMI（10''）+PLC+Magnetic coupling
Desktop controllerCB-DS-002BSiemens HMI（10''）+PLC+magnetic levitation
Desktop controllerCB-DS-003AAdvantech IPC（10''）+PLC+magnetic coupling
Desktop controllerCB-DS-003BAdvantech IPC（10''）++PLC+magnetic levitation
Desktop controllerCB-DS-003CAdvantech IPC（10''）+KirinX+magnetic coupling
Desktop controllerCB-DS-003DAdvantech IPC（10''）+KirinX+magnetic levitation
Desktop controllerCB-DS-006ADomestic IPC（10''）+PLC+magnetic coupling
Desktop controllerCB-DS-006BDomestic IPC（10''）+PLC+magnetic levitation
Desktop controllerCB-DS-006CDomestic IPC（10''）+KirinX+magnetic coupling
Desktop controllerCB-DS-006DDomestic IPC（10''）+KirinX+magnetic levitation

Integrated desktop

mixing system

ZCB-DS-007Simplified version, without weighing, with drive, adjustable speed with
speed display, without PLC
Desktop drive baseMOT-DS-001Magnetic coupling
Desktop drive baseMOT-DS-002Magnetic levitation

Note: The split mixing system consists of 3 parts: 1. Desktop controller. 2. Desktop drive base. 3. Mixing tank. (Standard  configuration includes mixing, weighing, and data logging functions.)


Mixing tank：

ProductNameSize(mm)AcrylicSingle-Layer
StainlessSteel		Jacketed
StainlessSteel
2LMixingtank160*160*130ZBLKDS02P001BLKDS02S001BLKDS02S002
5LMixingtank200*200*170BLKDS05P001BLKDS05S001BLKDS05S002
10LMixingtank240*240*220BLKDS10P001BLKDS10S001BLKDS10S002
20LMixingtank295*295*268BLKDS20P001BLKDS20S001BLKDS20S002
30 L Mixing tank331*331*357BLKDS30P001BLKDS30S001BLKDS30S002

Note: The standard configuration of Single-use split desktop mixing system includes mixing and weighing functions.


Optional modules

Product NameCat. No.
pH moduleBLK-DS-PH001 (120 mm)
pH moduleBLK-DS-PH002 (225 mm)
Cond moduleBLK-DS-CD001 (120 mm)
Cond moduleBLK-DS-CD002 (225 mm)
Temperature moduleBLK-DS-TM001
Printer moduleBLK-DS-PT001
Peristaltic pump module (gravimetric linkage)BLK-DS-PUMP001
Peristaltic pump module (acid-base linkage)BLK-DS-PUMP002
Temperature electrode holder (for acrylic)BLK-DS-TMZJ001
Temperature electrode holder (for single-layer stain-less steel)BLK-DS-TMZJ002
Temperature electrode holder (adapter jacket)BLK-DS-TMZJ003
pH electrode holder (for acrylic)BLK-DS-PHZJ001
pH electrode holder (for single-layer stainless steel)BLK-DS-PHZJ002
pH electrode holder (adapter jacket)BLK-DS-PHZJ003
Cond electrode holder (for acrylic)BLK-DS-CDZJ001
Cond electrode holder (for single-layer stainless steel)BLK-DS-CDZJ002
Cond electrode holder (adapter jacket)BLK-DS-CDZJ003


Services

Product NameCat. No.
DS (Desktop Mixing System) Standard Factory Acceptance Test (FAT)BDSFAT01
DS (Desktop Mixing System) Standard Site Acceptance Test (SAT)BDSSAT01
DS (Desktop Mixing System) Standard Installation and Operational Qualification (IQOQ) (Including Test Bag)BDSIQOQ02
DS (Desktop Mixing System) Standard Design Qualification (DQ)DSDQ02
DS (Desktop Mixing System) Standard Risk Assessment (RA)DSRA02
DS (Desktop Mixing System) Standard Computerized Systems Validation (CSV)DSCSV02

**Please be advised that this product is only available for sale and after-sales support in certain regions. For further details, kindly consult with your local sales representative. Thank you for your understanding.

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