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BioHub® Automated Bioprocess Analyzer

In the cell culture and fermentation processes of biopharmaceuticals, it is crucial to monitor the real-time "health status" and "metabolic activity" of the cells. The BioHub® Automated Bioprocess Analyzer provides fast and accurate measurement of key biochemical parameters in culture media, helping scientists and engineers to:

•    Guide process optimization: Precisely control nutrients, metabolites, ions, and products concentrations throughout the bioprocess to support the optimization of culture conditions.

•    Improve stability and repeatability: Standardized testing methods ensure data comparability across batches and time periods, minimizing human operational errors . The software supports historical data comparison between batches to verify process robustness and promptly identify anomalies.

•    Accelerate drug development and process scale-up: High-throughput testing accelerates the screening of optimal conditions, providing reliable data for evaluating cell line performance and process scale-up at different scales.


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Features Parameters Contact us

Features of BioHub® Automated Bioprocess Analyzer

1. High-performance analytical technology

•    Adopts new genetic chemical analysis technology, featuring high accuracy, high sensitivity, and a wide linear

range (supports 100-fold dilution).

•    Real-time response curves enable rapid assessment of data accuracy.


High-performance_analytical_technology.jpg



2. High efficiency and automation

•    Testing speed: CG220: 200 tests/h; CG300: 300 tests/h.

•    Supports automatic dilution, automatically retests when the linear range is exceeded or sample volume is insufficient.

•    Processes 18-40 samples simultaneously and allows STAT sample insertion.

3. Intelligent software system

•    Three-tier user permission management.

•    Database capacity up to 200,000 records with backup and restore functions.

•    Audit trail functionality to meet GMP compliance requirements.

4. Hardware design and maintenance

•    Compact, intelligent, and efficient design to meet stringent bioprocess monitoring needs.

•    Low maintenance and testing costs, high cost performance, with more reagents under continuous development.


Parameters of BioHub® Automated Bioprocess Analyzer

Performance ParametersCG220                                                                                      CG300
Detection PrincipleChemical reagent spectrophotometry: enzymes, substrates, special proteins
Testing Speed200 tests/h                                                                              300 tests/h
Number of Channels18 sample positions, continuous loading of
26 reagent positions, supports up to 26 types of tests
60 reaction cups, reusable		40 sample positions, continuous loading of
40 reagent positions, supports up to 40 types of tests
90 reaction cups, reusable
Single Testing Time<10 min
Sample CupSupports EP tubes, serum cups, centrifuge tubes, etc.
Temperature ControlReaction disk: 37 ± 0.1 °C; Reagent disk: 2-8 °C; Cooled sample area
Automated DilutionAutomatic dilution and retesting when results exceed the linear range or sample volume is insufficient
Cleaning SystemCascade cleaning for reagent and stirrer probes;
7-stage cleaning for reaction cups		Cascade cleaning for reagent and stirrer probes;
8-stage cleaning for reaction cups
SoftwareChinese and English versions available;  CFR 21 Part 11-compliant


Test Reagent

Device ModelProduct NameCat. No.Pack Size
CG220 & CG280Glucose Assay Kit (Dual Reagent)GLU-002240 tests/box
igG Assay KitIGG-001240 tests/box
Lactic Acid Assay KitLAC-002200 tests/box
Lactate Dehydrogenase Assay KitLDH-001200 tests/box
NH3 Assay KitNH3-001240 tests/box
Total Protein Assay KitTP-001240 tests/box
Glycerol Assay KitGLY-001240 tests/box
Cholesterol Assay KitCHO-001240 tests/box
Phosphate Assay KitPO4-001240 tests/box
Magnesium Assay KitMG-001240 tests/box
Iron Assay KitFE-001200 tests/box
Calcium Assay KitCA-001240 tests/box
Potassium Assay KitK2-001200 tests/box
Sodium Assay KitNA-001200 tests/box
CO2 Assay KitCO2-001240 tests/box
Pyruvate Assay KitPYR-001200 tests/box
Glutamic Acid Assay KitGLM-002200 tests/box
Glutamine Assay KitGLN-002200 tests/box
Methanol Assay KitACO-001200 tests/box
Ethanol Assay KitETOH-001240 tests/box
Acetic Acid Assay KitACID-001450 tests/box
CG300Glucose Assay Kit (Dual Reagent)GLU-300-002300 tests/box
igG Assay KitIGG-300-001300 tests/box
Lactic Acid Assay KitLAC-300-002300 tests/box
Lactate Dehydrogenase Assay KitLDH-300-001300 tests/box
NH3 Assay KitNH3-300-001300 tests/box
Total Protein Assay KitTP-300-001300 tests/box
Glycerol Assay KitGLY-300-001300 tests/box
Cholesterol Assay KitCHO-300-001300 tests/box
Phosphate Assay KitPO4-300-001300 tests/box
Magnesium Assay KitMG-300-001300 tests/box
Iron Assay KitFE-300-001300 tests/box
Calcium Assay KitCA-300-001300 tests/box
Potassium Assay KitK2-300-001300 tests/box
Sodium Assay KitNA-300-001300 tests/box
CO2  Assay KitCO2-300-001300 tests/box
Pyruvate Assay KitPYR-300-001300 tests/box
Glutamic Acid Assay KitGLM-300-002300 tests/box
Glutamine Assay KitGLN-300-002300 tests/box


Other Test Reagents

Device ModelProduct NameCat. No.Specification
CG220
CG280
CG300		Alkaline cleaning solutionCG-CL-001500 mL
Acid cleaning solutionCG-CL-002500 mL
Multiple calibration solutionCG-CAL-0015 mL
igG calibratorCG-CAL-IGG1 mL
Pyruvate calibration solutionCG-CAL-PYR1 mL
NH3 calibration solutionCG-CAL-NH31 mL
Multiple quality controlsCG-QC-0015 mL
igG quality controlCG-QC-IGG1 mL
Pyruvate quality controlCG-QC-PYR1 mL
NH3 quality controlCG-QC-NH31 mL
IQOQ reagent kitCG-IOQ-001/



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