Chrom-LinX^® Auto TH Chromatography Column

Name: Chrom-LinX ® Auto TH Chromatography Column
Brand: Bio-Link
Price: 100 USD

The Chrom-LinX® Auto TH Chromatography Column is designed for downstream purification in biopharmaceutical manufacturing. It enables intelligent packing through automated control software (Packing-LinX® Column Packing Station), reducing manual steps required for conventional columns. Column packing with the Slurry-LinX® series slurry tank allows most of the process to remain in a closed environment, minimizing the exposure and contamination risks of the chromatography resin and slurry.

Chrom-LinX® Auto TH columns are engineered to deliver excellent performance with a wide range of resins. They are compatible with the ChromaX® Chromatography Resins, and perform particularly well with high rigidity, high flow rate resins, such as Chromstar® FF and MaXtar®. The Packing-LinX® workstation presets the packing method for each resin type, which simplifies the packing process and improves production efficiency.

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Specifications Material Workstation Ordering Information Contact us

Chrom-LinX® Auto TH columns are low-pressure, axial compression chromatography columns which are suitable for process development and manufacturing of biopharmaceutical products. They are standardized equipment with ID of 450, 600, 800, 1000, 1200, 1400 and 1600 mm and column tube height of 700 mm (1000 mm customizable). The columns feature an optimized venting design for efficient air removal and easy cleaning of adapter. The distribution system design ensures uniform flow through the column bed. The packing process is controlled by the workstation software to achieve intelligent packing, unpacking, installation, dismantling and maintenance procedures, ensuring the stability and reproducibility of packing. The resin slurry is introduced via a bottom inlet and the adapter is driven upwards by a servo motor. After introducing a sufficient amount of slurry, the adapter moves down to pack the resin. The movement speed is controlled by software, with accuracy up to 1 mm, allowing precise control of bed height to form a uniform and consolidated bed.

Specifications of Chrom-LinX^® Auto TH Chromatography Column

Column Specifications

Column Inner Diameter (mm)	450	600	800	1000	1200	1400	1600
Column Tube Height (cm)	700
Maximum Operating Pressure	0.3 MPa (3 bar or 43.5 psi)
Operating Temperature (° C)	2-40
Bed Support (μm)	10/20

Material of Chrom-LinX^® Auto TH Chromatography Column

The construction materials of Chrom-LinX® Auto TH are suitable for biopharmaceutical manufacturing and conform to the ASME Bioprocessing Equipment Standard. Wetted polymeric materials and elastomers meet the requirements of USP <88> Biological Reactivity Tests, In Vivo and FDA 21 CFR Part 177. All materials are free from animal-derived ingredients and comply with the regulations in EMA/410/01 (Rev. 2). All parts used are traceable to the product batch. Wetted parts can withstand most chemical reagents commonly used in chromatography, such as buffers or organic reagents for adsorption, elution, washing and storage, as well as disinfectant solutions.

Component	Description
Column tube	Acrylic
Seals	EPDM+UPE
Distributor	PP
Top plate	316L stainless steel
Adapter	2205 stainless steel
Bed support net	316L stainless steel
Tubing/Fittings	316L stainless steel
Resin valve body	PP
Stand	304 stainless steel
Caster	Nylon + polyurethane

Packing-LinX^® Column Packing Station

The Packing-LinX® Column Packing Station enables 21 CFR Part 11 compliant packing operations. The touch screen interface offers an overview of the venting, packing, unpacking, and maintenance procedures. The packing process will stop automatically when the set compression factor or bed height is reached, or the operator can stop it manually at any time.

Ordering Information of Chrom-LinX^® Auto TH Chromatography Column

**Please be advised that this product is only available for sale and after-sales support in certain regions. For further details, kindly consult with your local sales representative. Thank you for your understanding.

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Want to know more about BioLink bioprocessing products? Feel free to contact BioLink now!

Email

info@biolink.com

Phone

0086-400-058-9000

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Chrom-LinX® Auto TH Chromatography Column

Specifications of Chrom-LinX® Auto TH Chromatography Column

Material of Chrom-LinX® Auto TH Chromatography Column

Packing-LinX® Column Packing Station

Ordering Information of Chrom-LinX® Auto TH Chromatography Column