Chrom-LinX^® Laboratory Scale Empty Chromatography Column

Name: Chrom-LinX ® Laboratory Scale Empty Chromatography Column
Brand: Bio-Link

Chrom-LinX® laboratory scale empty chromatography column is a family of chromatography column designed for simple operation, high pressure resistance and flexible adjustment, which are suitable for process development, process verification, quality testing and preparative small-scale sample purification.

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Features Characteristics Chemicals Instructions Specifications Video Contact us

Please be advised that this product is only available for sale and after-sales support in certain regions. For further details, kindly consult with your local sales representative. Thank you for your understanding.

Features and Benefits of Chrom-LinX^® Laboratory Scale Empty Chromatography Column

User-friendly design: Ergonomically design the components for easy grasping and handling
Clear view: Equipped with a measurement scale of glass tube for easy to predict and reach a predefined bed height and improving process reproducibility
High pressure resistance: compatible with common resins of different particle sizes allowing operation up to 20 bar* (2 MPa, 290 psi) pressure
Various sizes: Glass tubes with inner diameter (i.d.) of 10 mm, 16 mm, 26 mm or 50 mm, and bed height of 200 mm, 400 mm, 700 mm or 1000 mm provide a wide range of column volumes
High flexibility: Equipped with single/double adjustable capital for flexible expansion of column volumes
Easy to clean: Each component for easy assembling removing and cleaning
Compatibility: Supplied with tubing and connectors suitabling for a variety of common laboratory tomographic systems

Empty Chromatography Column

Fig 1. Chrom-LinX^® laboratory grade empty chromatography columns

*The columns withstands pressures up to 7 bar (0.7 MPa, 101.5 psi) with 50 mm inner diameter.

Product Characteristics of Chrom-LinX^® Laboratory Scale Empty Chromatography Column

Chrom-LinX® Laboratory Scale Empty Chromatography Columns are available in two designs: single adjustable capital and double adjustable capital. The design of single adjustable capital mainly consists of a adjustable capital, a chromatography column tube and a fixed capital. The design of double adjustable capital replaces the fixed capital with an adjustable capital to extend the column volume (Fig 2).

Chrom-LinX® Laboratory Scale Empty Chromatography Columns are equipped with 10 μm net ring (5 μm net ring being also optional), which are compatible with common resins of different particle sizes.

Glass Chromatography Column

Fig 2. Components of the Chrom-LinX^® laboratory grade empty columns

Chemical Resistance of Chrom-LinX^® Laboratory Scale Empty Chromatography Column

Chrom-LinX^® laboratory grade empty chromatography columns are made of biocompatible materials with good chemical tolerance. The columns can be used in aqueous solutions and almost all the organic solvents commonly used in liquid chromatography of macromolecules. The columns intolerant of chlorinated hydrocarbons, acetone and other ketones, aliphatic esters, and phenol. The columns are not allowed to use the solution containing more than 2 M NaOH, 1 M HCl, other strong mineral acids, or 75% acetic acid.

No.	Name
1	Adjustable capital
2	Column tube
3	Fixed capital
4	O-ring
5	Support screen
6	Net ring
7	Tubing

Large Glass Chromatography Columns

Fig 3. Details of the Chrom-LinX^® laboratory grade empty columns

Instructions of Chrom-LinX^® Laboratory Scale Empty Chromatography Column

Chrom-LinX^® laboratory grade empty chromatography column may be used at temperatures from 4° C to 40° C and pressures up to 20 bar (2 MPa, 290 psi) with inner diameters of 10 mm, 16 mm and 26 mm, and 7 bar (0.7 MPa, 101.5 psi) with an inner diameter of 50 mm.

Always clean the column and components with purified water before using.

When packing the column, the double top cap can be rotated, and the threaded shaft moves axially. This operation makes the resins easy to compress. If necessary, column packing can be performed using either a packing tube (Fig 4) or an extra column tube attached with a packing connector.

Packed Column Chromatography

Packing tube operations of the Chrom-LinX^® laboratory grade empty columns

Specifications of Chrom-LinX^® Laboratory Scale Empty Chromatography Column

Empty column

Table 1. Parameter of the Chrom-LinX^® laboratory scale empty column

Product code*	Column**	Column height (mm)	Bed height (mm)	Bed volume (ml)
2110-1111	Chrom-LinX^® 10/200	200	0-155	0-12
2110-1112	Chrom-LinX^® 10/400	400	225-355	18-28
2110-1122	Chrom-LinX^® 10/400P	400	0-355	0-28
2116-1111	Chrom-LinX^® 16/200	200	0-155	0-31
2116-1112	Chrom-LinX^® 16/400	400	225-355	45-71
2116-1122	Chrom-LinX^® 16/400P	400	0-355	0-71
2116-1113	Chrom-LinX^® 16/700	700	525-655	105-132
2116-1123	Chrom-LinX^® 16/700P	700	355-655	71-132
2116-1114	Chrom-LinX^® 16/1000	1000	825-955	166-192
2116-1124	Chrom-LinX^® 16/1000P	1000	655-955	132-192
2126-1111	Chrom-LinX^® 26/200	200	0-155	0-82
2126-1112	Chrom-LinX^® 26/400	400	225-355	119-188
2126-1122	Chrom-LinX^® 26/400P	400	0-355	0-188
2126-1113	Chrom-LinX^® 26/700	700	525-655	278-347
2126-1123	Chrom-LinX^® 26/700P	700	355-655	188-347
2126-1114	Chrom-LinX^® 26/1000	1000	825-955	438-507
2126-1124	Chrom-LinX^® 26/1000P	1000	655-955	347-507
2150-1111	Chrom-LinX^® 50/200	200	0-155	0-304
2150-1112	Chrom-LinX^® 50/400	400	225-355	441-697
2150-1122	Chrom-LinX^® 50/400P	400	0-355	0-697
2150-1113	Chrom-LinX^® 50/700	700	525-655	1030-1285
2150-1123	Chrom-LinX^® 50/700P	700	355-655	697-1285
2150-1114	Chrom-LinX^® 50/1000	1000	825-955	1619-1874
2150-1124	Chrom-LinX^® 50/1000P	1000	655-955	1285-1874

* The specifications of the following item numbers are 1 per package

** The ''P'' after the column stands for equipped with two adjustable capitals

Packing tube

Product code	Product name	No. per pack
2720-1001	10 packing tube	1
2720-1601	16 packing tube	1
2720-2601	26 packing tube	1
2720-5001	50 packing tube	1

Spare and accessory parts

Product code *	10mm	16mm	26mm	50mm	No. per pack
O-ring	2719-1003	2719-1603	2719-2603	2719-5003	5
Support screen	2721-1001	2721-1601	2721-2601	2721-5001	5
Net ring, 10 μm	2724-1011	2724-1611	2724-2611	2724-5011	5
Net ring, 5 μm	2724-1052	2724-1652	2724-2652	2724-5052	5
Adjustable capital	2730-1001	2730-1601	2730-2601	2730-5001	1
Column tube 200mm	2731-1001	2731-1601	2731-2601	2731-5001	1
Column tube 400mm	2731-1002	2731-1602	2731-2602	2731-5002	1
Column tube 400mm, P	2731-1012	2731-1612	2731-2612	2731-5012	1
Column tube 700mm	-	2731-1603	2731-2603	2731-5003	1
Column tube 700mm, P	-	2731-1613	2731-2613	2731-5013	1
Column tube 1000mm	-	2731-1604	2731-2604	2731-5004	1
Column tube 1000mm, P	-	2731-1614	2731-2614	2731-5014	1
Fixed capital	2732-1001	2732-1601	2732-2601	2732-5001	1
Union, 10-32	2726-1001	2726-1001	2726-1001	-	10
Union, 10-32 to 5-16	-	-	-	2726-1002	10
Union, 10-32 to M6	-	-	-	2726-1003	10
Union, 10-32 to luer taper	2726-1004	2726-1004	2726-1004	-	10
Union, 3-16	-	-	-	2726-3101	10
Union, 1-8	-	-	-	2726-1801	10
Stop plug, male, 10-32	2727-1001	2727-1001	2727-1001	-	10
Stop plug, female, 10-32	2727-1002	2727-1002	2727-1002	-	10
Bi-pass, 10-32	2728-1001	2728-1001	2728-1001	-	10
Bi-pass, M6	-	-	-	2728-0601	10
Ferrules for 1/16"	2725-1601	2725-1601	2725-1601	-	5
Ferrules for 1/8"	-	-	-	2725-1801	5
PEEK tubing, 0.75 mm i.d.	2729-1601	2729-1601	2729-1601	-	2 m
PEEK tubing, 2 mm i.d.	-	-	-	2729-1801	2 m
Capillary tubing, 0.75 mm i.d.	2733-1601	2733-1601	2733-1601	-	2 m
Capillary tubing, 1.6 mm i.d.	-	-	-	2733-1801	2 m
Accessory kit**	2723-1001	2723-1601	2723-2601	2723-5001	1

* The "P" after the column stands for equipped with two adjustable capitals.

** The accessory kit includes 2 stop plugs (female), 2 union, 2 O-ring and 2 support screen (10 μm).