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BioHub® Single-use Sampling Bottle

Product sampling is necessary and critical for cell culture and other operations in biopharmaceutical processes. Samples collected through BioHub® Single-use Sampling Bottle can be used to determine critical purity attributes, such as sterility, endotoxin levels, bioburden, and important cell culture parameters including metabolites, nutrient levels, pH, and osmolarity. BioHub® Single-use Sampling Bottle provides a preassembled sampling solution.


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In biopharmaceutical processes, product sampling is critical for cell culture, separation and purification, bulk drug substance storage, and final product filling. Samples collected through the BioHub® Single-use Sterile Sampling System can be used to determine critical purity attributes, such as sterility, endotoxin levels, and bioburden, and important cell culture parameters including metabolites, nutrient levels, pH, and osmolarity. BioHub® Single-use Sterile Sampling System provides a pre-assembled, pre-sterilized, and pre-validated solution with highly customized designs tailored to meet various application needs. The system enables closed, sterile, and consistent sampling, ensuring safe, reliable, and efficient process monitoring.




Features of BioHub® Single-use Sterile Sampling System

Product Features 

  • 2 mm 316L stainless steel needle with overmolded tubing for assurance of airtightness and sterility. 

  • Available in two types of sampling containers: bags and bottles, covering a variety of sampling needs in the stainless steel equipment process. 

  • Highly customizable design with multi-port Luer 3-way valve to effectively reduce residual and rinsing volume. 

  • Comprehensive validation documents.


Sampling Bottle 

  • Volume range: 20 mL to 250 mL. 

  • Made of PC material, with high transparency and graduations, accuracy ±5%, suitable for use in the temperature range of − 80 ℃ to 121 ℃ . 

  • Working pressure: single-needle, multi-bottle products: 0.5 bar. 

Note: If the sampling bottle is used as a freezing container, it can be used in conjunction with the BioLink torque wrench kit. For details, please consult your local sales representative.

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Validation Documents of BioHub® Single-use Sampling Bottle

  • 100% integrity testing

  • USP <665>, Extractable testing

  • USP <88> , Class VI plastics

  • USP <87>, Cytotoxicity

  • USP <788>, Particulate Matter in Injections

  • USP <85>, Bacterial Endotoxins

  • ISO 11137, Sterility testing

  • ISO 10993-4, Hemolysis testing




Specifications of BioHub® Single-use Sampling Bottle

Figure_6.png

    Figure. Schematic diagram of manifold sampling bottles (with manifold Luer 3-way valve)


Sampling bottles (with manifold Luer 3-way valve)



Cat. No.VolumeInlet TubingOutlet Tubing
TSTG-ST03720 mL2 mm needle, silicone tubing,
ID 3.2 mm*OD 6.4 mm,
25 cm in length, with metal ring for sterile
disconnection
Silicone tubing,
ID 3.2 mm*OD 6.4 mm,
25 cm in length, with vent filter
TSTG-ST03850 mL
TSTG-ST039125 mL
TSTG-ST040250 mL
TSTG-ST0412X20 mL2 mm needle, silicone tubing,
ID 3.2 mm*OD 6.4 mm,
25 cm in length, with metal ring for sterile
disconnection
Silicone tubing,
ID 3.2 mm*OD 6.4 mm,
25 cm in length, with vent filter
TSTG-ST0422X50 mL
TSTG-ST0432X125 mL
TSTG-ST0442X250 mL
TSTG-ST0453X20 mL2 mm needle, silicone tubing,
ID 3.2 mm*OD 6.4 mm,
25 cm in length, with metal ring for sterile
disconnection
Silicone tubing,
ID 3.2 mm*OD 6.4 mm,
25 cm in length, with vent filter
TSTG-ST0463X50 mL
TSTG-ST0473X125 mL
TSTG-ST0483X250 mL
TSTG-ST0495X20 mL2 mm needle, silicone tubing,
ID 3.2 mm*OD 6.4 mm,
25 cm in length, with metal ring for sterile
disconnection
Silicone tubing,
ID 3.2 mm*OD 6.4 mm,
25 cm in length, with vent filter
TSTG-ST0505X50 mL
TSTG-ST0515X125 mL
TSTG-ST0525X250 mL
TSTG-ST05620 mL2 mm needle, silicone tubing,
ID 3 mm*OD 6 mm,
25 cm in length, with metal ring for sterile
disconnection
Silicone tubing,
ID 3 mm*OD 6 mm,
25 cm in length, with vent filter
TSTG-ST05750 mL
TSTG-ST058125 mL
TSTG-ST059250 mL
TSTG-ST0602X20 mL2 mm needle, silicone tubing,
ID 3 mm*OD 6 mm,
25 cm in length, with metal ring for sterile
disconnection
Silicone tubing,
ID 3 mm*OD 6 mm,
25 cm in length, with vent filter
TSTG-ST0612X50 mL
TSTG-ST0622X125 mL
TSTG-ST0632X250 mL
TSTG-ST0643X20 mL2 mm needle,Silicone tubing,
ID 3 mm*OD 6 mm,
25 cm in length, with metal ring for sterile
disconnection
Silicone tubing,
ID 3 mm*OD 6 mm,
25 cm in length, with vent filter
TSTG-ST0653X50 mL
TSTG-ST0663X125 mL
TSTG-ST0673X250 mL
TSTG-ST0685X20 mL2 mm needle,Silicone tubing,
ID 3 mm*OD 6 mm,
25 cm in length, with metal ring for sterile
disconnection
Silicone tubing,
ID 3 mm*OD 6 mm,
25 cm in length, with vent filter
TSTG-ST0695X50 mL
TSTG-ST0705X125 mL
TSTG-ST0715X250 mL


Figure_7.png

Figure. Schematic diagram of manifold sampling bottles (with standard barbed connector)


Sampling bottles (with standard barbed connector)


Cat. No.VolumeInlet TubingOutlet Tubing
TSBG-ST0035X125mL2 mm sampling needle,silicone tubing,
ID3.2mm*OD6.4mm,20 cm in length,
with a sleeve for sterile disconnection
Silicone tubing,ID3.2mm*OD6.4mm,15
cm in length, with vent filter
TSBG-ST00710X125mL
TSBG-ST0045X125mL2 mm sampling needle,thermoplastic
tubing,ID3.2mm*OD6.4mm,30 cm in
length
Thermoplastic tubing,
ID3.2mm*OD6.4mm,15 cm in length,
with vent filter
TSBG-ST00810X125mL


Ordering Information


Figure_100.png

Figure. Schematic diagram of manifold sampling bottles (with standard barbed connector)


Cat. No.VolumeInlet TubingOutlet Tubing
TSBG-ST0015X125mLLuer connector,silicone tubing,
ID6.4mm*OD6.4mm,20 cm in length,
with a sleeve for sterile disconnection
Silicone tubing,ID3.2mm*OD6.4mm,15cm in length,with vent filter
TSBG-ST00510X125mL
TSBG-ST0025X125mLLuer connector,thermoplastic tubing,
ID3.2mm*OD6.4mm,30 cm in length
Thermoplastic tubing,
ID3.2mm*OD6.4mm,15 cm in length,
with vent filter
TSBG-ST00610X125mL

**Please be advised that this product is only available for sale and after-sales support in certain regions. For further details, kindly consult with your local sales representative. Thank you for your understanding.

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