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CruclixTM Hollow Fiber Filter

CruclixTM Hollow Fiber Filters from BioLink are designed for tangential flow membrane separations,  including two categories: microfiltration and ultrafiltration.  CruclixTM Hollow Fiber filters offer a range of sizes from small to large, support applications from drugdevelopment,pilot scale to commercial manufacturing.CruclixTMHollow Fiber Filters offer both standard models for regular environments and modelsautoclavable, to meet the requirements of different usage scenarios.

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Key applications of CruclixTM Hollow Fiber Filter

  • Lysate clarification

  • Cell concentration, clarification, diafiltration

  • Virus purification, concentration, diafiltration

  • Recombinant protein purification,concentration, diafiltration

  • Inclusion body clarification and renaturation

  • Nanoparticle diafiltration and aeparation

  • Liposome concentration and diafiltration


Why Choose CruclixTM Hollow Fiber Filtration?

Excellent Performance

  • Validated hydrophilic polyethersulfone(mPES) membrane

  • Asymmetric pore structure

  • High throughput, low differential pressure, high loading capacity and long shelf lifeEasy wetting with water for rapid integrity testing

  • Excellent chemical compatibility, suitable for solutions with pH 1-14, including NaOH solutionLow adsorption of target products, ensuring high recovery rate

  • Full range of specifications for easy scale-up


Regulatory Compliance

CruclixTM Hollow Fiber filters, have been reviewed and approved by authoritative institutions andcomply with the 1s0 13485 quality system. They are developed, designed, and manufactured underthis quality management system, All products are manufactured in a Class 7 cleanroom accordingto lS0 standards and are subject to strict quality inspection. Only those that pass the inspection arereleased with a quality certificate. All raw materials and manufacturing processes used in the production can be traced by the serialnumber iS/N code), The hollow fibers used in the column are made from animal-free materials, andall fluid path materials have been tested and meet the USP <88> Class Vl biocompatibility standards


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